| Health / Medical Topics |
9H-Purine-6Thio-98D
An antimetabolite analogue of purine with antineoplastic and immuno-suppressant properties. 9H-Purine-6Thio-98D substitutes for the normal nucleoside and fraudulently incorporates into DNA and inhibits de novo purine synthesis, thereby inducing cell death. In vivo, this agent, also known as 6MP-arabinoside, may occur as a metabolite of the antineoplastic agent mercaptopurine. (NCI Thesaurus)
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