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A2M wt Allele
Human A2M wild-type allele is located in the vicinity of 12p13.31 and is approximately 49 kb in length. This allele, which encodes alpha-2-macroglobulin protein, plays a role in various processes as a protease inhibitor. Mutations in this gene are associated with alpha-2-macroglobulin deficiency and susceptibility to Alzheimer disease. (NCI Thesaurus)
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This gene has activity as a protease inhibitor.
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