| Health / Medical Topics |
Aberrant Crypt Foci of the Mouse Intestinal Tract
Definition 1
An intestinal tract lesion where one or more crypts are enlarged and elevated above the surrounding mucosa. Additionally, these crypts often have a slit-shaped luminal opening. Cells are methylene blue positive on whole-mount sections of the intestinal mucosa. (NCI Thesaurus)
Definition 2
Cells are methylene blue positive on whole mounts, cells have basophilic cytoplasm on H and E stain, and may have Beta-catenin staining in the nucleus. (NCI Thesaurus/MMHCC)
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