| Health / Medical Topics |
ABT-510
Definition 1
A substance being studied in the treatment of cancer. It is a type of angiogenesis inhibitor. (NCI Dictionary)
Definition 2
A synthetic peptide that mimics the anti-angiogenic activity of the endogenous protein thrombospondin-1 (TSP-1). ABT-510 inhibits the actions of several pro-angiogenic growth factors important to tumor neovascularization; these pro-angiogenic growth factors include vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF)), hepatocyte growth factor (HGF), and interleukin 8 (IL-8). (NCI Thesaurus)
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