ADAM11 wt Allele

Human ADAM11 wild-type allele is located in the vicinity of 17q21.3 and is approximately 21 kb in length. This allele, which encodes ADAM11 protein, plays a role in integrin binding. Expression of the ADAM 11 gene is disrupted in cancers such as breast and ovarian cancer due to gene rearrangements. (NCI Thesaurus)

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ADAM11 Gene

This gene plays a role in cell-cell and cell-matrix interactions.

ADAM10 wt Allele

Human ADAM10 wild-type allele is located in the vicinity of 15q22 and is approximately 155 kb in length. This allele, which encodes…

ADAM10 Gene

This gene plays a role in the regulation of protein cleavage.

ADAM Type Metalloprotease Domain

ADAMs are transmembrane proteins containing both a disintegrin and a metalloprotease domain. Two thirds of the proteins with an ADAM type metalloprotease…

ADAM Family Protein

The ADAM family consists of transmembrane proteins that contain a disintegrin and metalloprotease domain. By virtue of these domains they have…

ADAM Family Gene

ADAMs (A Disintegrin and Metalloproteinase Domain) are membrane-anchored proteases that regulate cell behavior by proteolytically modifying the cell surface and extracellular…