Adamantinoma

Definition 1

A low grade malignant biphasic tumor characterized by a variety of morphologic patterns, most commonly epithelial cells surrounded by a relatively bland spindle-cell osteofibrous component. The tibia is the most commonly affected site. (WHO 2002) (NCI Thesaurus)

Definition 2

A low-grade malignant neoplasm composed of epithelial cells and a spindle cell osteo-fibrous proliferation. (NCI Thesaurus/CDISC)

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ADAM8 wt Allele

Human ADAM8 wild-type allele is located in the vicinity of 10q26.3 and is approximately 14 kb in length. This allele, which encodes…

ADAM8 Gene

This gene is involved in the mediation of proteolysis.

ADAM17 wt Allele

Human ADAM17 wild-type allele is located within 2p25 and is approximately 66 kb in length. This allele, which encodes ADAM17 protein, is…

ADAM17 Gene

This gene plays a role in the cleavage of membrane proteins, resulting in the release of their extracellular domains from cells. …

ADAM15 wt Allele

Human ADAM15 wild-type allele is located in the vicinity of 1q21.3 and is approximately 11 kb in length. This allele, which encodes…

ADAM15 Gene

This gene is involved in the restructuring of the mesangial matrix.