Adenocarcinoma with Spindle Cell Metaplasia

An invasive adenocarcinoma characterized by the presence of focal or extensive neurosecretory cell differentiation with the formation of organoid patterns.

Consists of various combinations of papillary, acinar and solid structures.

An invasive adenocarcinoma characterized by focal or extensive cartilage and/or bone formation.

An invasive adenocarcinoma characterized by focal or extensive transformation of the malignant glandular cells to cells with abundant, usually granular eosinophilic…

An adenocarcinoma which has metastasized from an unknown primary anatomic site.

Compared to adenomas, adenocarcinomas show greater cytological atypia, increased frequency of mitoses, regional variation in growth pattern, more papillary structures, have size…