ADRBK1 wt Allele

Human ADRBK1 wild-type allele is located within 11q13 and is approximately 20 kb in length. This allele, which encodes beta-adrenergic receptor kinase 1 protein, plays a role in the phosphorylation of the activated form of the beta-adrenergic and related G-protein-coupled receptors. This modification results in mediation of agonist-specific desensitization observed at high agonist concentrations. Elevated ADRBK1 gene expression is associated with impaired cardiac function and heart failure. (NCI Thesaurus)

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ADRBK1 Gene

This gene is involved in signal transduction.

ADRB2 wt Allele

Human ADRB2 wild-type allele is located within 5q31-q32 and is approximately 2 kb in length. This allele, which encodes beta-2 adrenergic receptor…

ADRB2 Gene

This gene is involved in maintaining the integrity and rate of G protein-coupled receptor signal transduction.

ADRB1 wt Allele

Human ADRB1 wild-type allele is located within 10q24-q26 and is approximately 2 kb in length. This allele, which encodes beta-1 adrenergic receptor…

ADRB1 Gene

This gene plays a role in neuronal G protein-coupled receptor signal transduction that modulates the physiological effects of epinephrine and norepinephrine. …

ADRA2C wt Allele

Human ADRA2C wild-type allele is located in the vicinity of 4p16 and is approximately 2 kb in length. This allele, which encodes…