ADRBK2 wt Allele

Human ADRBK2 wild-type allele is located within 22q11 and is approximately 159 kb in length. This allele, which encodes beta-adrenergic receptor kinase 2 protein, is involved in the phosphorylation of the activated form of the beta-adrenergic and related G-protein-coupled receptors. This modification results in mediation of agonist-specific desensitization observed at high agonist concentrations. Certain allelic variants of the ADRBK2 gene are associated with susceptibility to bipolar disorder. (NCI Thesaurus)

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ADRBK2 Gene

This gene plays a role in signal transduction.

ADRBK1 wt Allele

Human ADRBK1 wild-type allele is located within 11q13 and is approximately 20 kb in length. This allele, which encodes beta-adrenergic receptor kinase…

ADRBK1 Gene

This gene is involved in signal transduction.

ADRB2 wt Allele

Human ADRB2 wild-type allele is located within 5q31-q32 and is approximately 2 kb in length. This allele, which encodes beta-2 adrenergic receptor…

ADRB2 Gene

This gene is involved in maintaining the integrity and rate of G protein-coupled receptor signal transduction.

ADRB1 wt Allele

Human ADRB1 wild-type allele is located within 10q24-q26 and is approximately 2 kb in length. This allele, which encodes beta-1 adrenergic receptor…