Health / Medical Topics

    Alpha Heavy Chain Disease

    A clonal disorder, also known as immunoproliferative small intestinal disease or Mediterranean lymphoma, characterised by the secretion of a defective alpha heavy chain. It predominantly affects young people in the Mediterranean region. It involves the small intestine, and patients usually present with malabsorption syndrome, abdominal pain, weight loss, and fever. There is extensive villous atrophy of the small intestinal mucosa, which is heavily infiltrated by small lymphocytes and plasma cells. The small intestinal morphologic changes are consistent with a mucosa-associated lymphoid tissue lymphoma (MALT lymphoma). Alpha heavy chain disease frequently progresses to large B-cell lymphoma, and normally has a poor prognosis. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    Granules found in several types of cells, especially platelets, where they are the most numerous type of granule; contain secretory proteins. …
    The determination of the ratio of alpha glutathione-s-transferase compared to creatinine present in a sample. The measurement may be expressed as a…
    The determination of the amount of alpha glutathione-s-transferase present in a sample.
    The determination of the amount of alpha glucuronidase present in a sample.
    A potent alpha galactosylceramide modified from marine-sponge that stimulates the immune system to exhibit antitumor activity.
    A vaccine consisting of plasmid DNA encoding alpha fetoprotein. After vaccination, expressed alpha fetoprotein may stimulate a cytotoxic T lymphocyte (CTL) response…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact