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Alpha Naphthyl Esterase Staining Method
A cytochemical staining technique using the alpha-naphthyl esterase staining method or a nonspecific esterase staining method to identify and quantify monoblasts and monocytes and to detect esterase activity. The esterase enzyme contained within monocytes and macrophages reacts strongly with the substrate alpha-naphthyl butyrate. The test is useful in diagnosis of acute leukemias. It marks immature monocytes, and thus is useful in the diagnosis of acute myelogenous leukemia of monocytic type. (NCI Thesaurus)
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