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A synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent…

A substance being studied in the treatment of several types of cancer. It stops cells from dividing and may kill cancer…

The Alvin J Siteman Cancer Center is dedicated to advancing new approaches to cancer prevention, diagnosis, and treatment through research. It became…

A synthetic trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid receptors,…

The white myelinated fibers in the hippocampus adjacent to the wall of the lateral ventricle.

The hydrochloride salt of alvespimycin, an analogue of the antineoplastic benzoquinone antibiotic geldanamycin. Alvespimycin binds to HSP90, a chaperone protein that aids…