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Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change Questionnaire
Definition 1
A standardized rating scale developed by Lon S. Schneider in 1997 to evaluate a clinically relevant change in an individual's Alzheimer's Disease symptoms. This instrument consists of an interview that is given to both the patient and their caregiver by a clinician at a baseline visit and then is repeated at the 2, 6, and 12 month visits. Based on the information gather at the 2, 6, and 12 month visits, the clinician rates the patients change from baseline on a 7 increment scale ranging from 'Marked Improvement' to 'Marked Worsening.' (NCI Thesaurus)
Definition 2
Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change (ADCS-CGIC) (Schneider LS, Olin JT, Doody RS, Clark CM, Morris JC, Reisberg B, Schmitt FA, Grundman M, Thomas RG, Ferris SH, and the Alzheimer's Disease Cooperative Study. Validity and Reliability of the Alzheimer's Disease Cooperative Study-Clinical Global Impression of Change. Alzheimer Disease and Associated Disorders. 1997; 11(2):S22-S32). (NCI Thesaurus/CDISC)
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