Amifampridine

An organic compound derived from pyridine with potassium channel inhibition activity. Amifampridine inhibits potassium channel efflux, increasing the duration of the action potential, which results in an increase in the duration of calcium channel opening and enhanced acetylcholine (ACh) release. Increased ACh availability at the motor end plate allows muscles to contract. (NCI Thesaurus)

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Amidophosphoribosyltransferase Inhibitor

Any substance that inhibits amidophosphoribosyltransferase, an enzyme that catalyzes the commiting step on de novo purine synthesis. Inhibition of amidophosphoribosyltransferase inhibits DNA…

Amidophosphoribosyltransferase

Amidophosphoribosyltransferase (517 aa, ~57 kDa) is encoded by the human PPAT gene. This protein is involved in purine biosynthesis.

Amidino TIC

One of 800 terephthalanilides synthesized and tested preclinically in the late 1950's and early 1960's. Chosen in the 1990's for further…

AMHR2 wt Allele

Human AMHR2 wild-type allele is located within 12q13 and is approximately 8 kb in length. This allele, which encodes anti-Muellerian hormone type-2…

AMHR2 Gene

This gene plays a role in gonadal development.

AMH wt Allele

Human AMH wild-type allele is located in the vicinity of 19p13.3 and is approximately 3 kb in length. This allele, which encodes…