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Aminoglycoside antibiotic
Pronunciation
Definition 1
A substance that works against many types of bacteria and includes streptomycin, gentamicin, and neomycin. An aminoglycoside antibiotic is used to treat bacterial infections. (NCI Dictionary)
Definition 2
Any antibiotic containing amino-modified sugars originally isolated from various Streptomyces and Micromonospora species. Aminoglycoside antibiotics bind to the 16S RNA of the bacterial 30S ribosomal subunit, inhibiting translation and protein synthesis. Aminoglycoside use is associated with ototoxicity, neurotxicity and nephrotoxicity. (NCI Thesaurus)
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