Amoxapine

A tricyclic antidepressant of the dibenzoxazepine class. Amoxapine exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerve endings and blocks the response of dopamine receptors to dopamine. This drug is used to treat symptoms of depression and may cause tardive dyskinesia. Amoxapine also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which accounts for many of the side effects seen with this agent. (NCI Thesaurus)

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Amount Recovered Over Dosing Interval Normalized by Weight

The cumulative amount recovered from the specimen type specified in PPSPEC between doses (TAU) divided by weight.

Amount Recovered Over Dosing Interval Normalized by Surface Area

The cumulative amount recovered from the specimen type specified in PPSPEC between doses (TAU) divided by surface area.

Amount Recovered Over Dosing Interval Normalized by Body Mass Index

The cumulative amount recovered from the specimen type specified in PPSPEC between doses (TAU) divided by body mass index.

Amount Recovered Over Dosing Interval

The cumulative amount recovered from the specimen type between doses (TAU).

Amount Recovered Normalized by Weight

The cumulative amount recovered from the specimen type, from dosing to end of the current collection interval divided by the weight. …

Amount Recovered Normalized by Surface Area

The cumulative amount recovered from the specimen type, from dosing to end of the current collection interval divided by the surface…