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    AMYOTROPHIC LATERAL SCLEROSIS

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    Thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord; results in progressive muscle atrophy that starts in the limbsplay

    Synonyms:

    ALS; amyotrophic lateral sclerosis; Lou Gehrig's disease

    Classified under:

    Nouns denoting stable states of affairs

    Hypernyms ("amyotrophic lateral sclerosis" is a kind of...):

    nervous disorder; neurological disease; neurological disorder (a disorder of the nervous system)

    induration; sclerosis (any pathological hardening or thickening of tissue)

    Credits

     Context examples: 

    Dysphagia is prevalent among older people in particular (30%–40% of the elderly people admitted to hospitals or care homes) and patients with neurological or neurodegenerative disorders and diseases such as Alzheimer’s, Parkinson’s or multiple sclerosis, amyotrophic lateral sclerosis, cerebral palsy, or strokes.

    (Scientists designed the first test to detect dysphagia, University of Granada)

    Scientists from the University of Cambridge and University of Toronto have identified the molecular mechanism that leads to the death of neurons in amyotrophic lateral sclerosis (also known as ALS or motor neurone disease) and a common form of frontotemporal dementia.

    (Mechanism behind neuron death in motor neurone disease and frontotemporal dementia discovered, University of Cambridge)

    Amyotrophic lateral sclerosis (ALS) is a progressive, lethal, degenerative disorder of motor neurons.

    (Amyotrophic Lateral Sclerosis Pathway, NCI Thesaurus/KEGG)


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