| Health / Medical Topics |
Androgen-independent
Pronunciation
Describes the ability of tumor cells to grow in the absence of androgens (hormones that promote the development and maintenance of male sex characteristics). Many early prostate cancers require androgens for growth, but advanced prostate cancers are often androgen-independent. (NCI Dictionary)
YOU MAY ALSO LIKE
Administration of male hormones to produce a clinical effect.
Treatment to suppress or block the production or action of male hormones. This is done by having the testicles removed, by taking…
Androgen response element is the target binding element for activated androgen receptor homodimer. The consensus sequence for this high-affinity androgen receptor-binding…
Describes cells that have a protein that binds to androgens (male hormones). Cancer cells that are androgen receptor positive may need androgens…
A locked nucleic acid (LNA)-based antisense oligonucleotide targeting the androgen receptor (AR) mRNA, with potential antineoplastic activity. Upon administration, EZN-4176 is hybridized…
A small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity. ARN-509 binds to AR in target tissues thereby preventing androgen-induced…
