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ANGIOGENESIS
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The formation of new blood vessels
Classified under:
Nouns denoting natural processes
Hypernyms ("angiogenesis" is a kind of...):
development; growing; growth; maturation; ontogenesis; ontogeny ((biology) the process of an individual organism growing organically; a purely biological unfolding of events involved in an organism changing gradually from a simple to a more complex level)
Context examples:
This may result in the inhibition of angiogenesis and cell proliferation in tumor cells in which these kinases are upregulated.
(Multikinase Inhibitor 4SC-203, NCI Thesaurus)
Nesvacumab binds to ANG2 and interferes with the interaction between Ang2 and its receptor TEK tyrosine kinase (Tie2), which may inhibit tumor cell angiogenesis and tumor cell proliferation.
(Nesvacumab, NCI Thesaurus)
Processes and mechanisms that block angiogenesis.
(Negative Regulation of Angiogenesis, NCI Thesaurus)
Implicated in control of feeding, energy balance, and secretion of GNRH, NPY may also regulate angiogenesis.
(Neuropeptide Y, NCI Thesaurus)
Binding to semaphorin 3A, PLGF-2, VEGF-165, and VEGF-B, Isoform 1 appears to mediate chemorepulsion by semaphorins, to increase VEGF-165 binding to KDR, and to regulate VEGF-induced angiogenesis.
(Neuropilin 1, NCI Thesaurus)
CXCLs are small cytokines in the CXC chemokine family that are overexpressed in certain cancers; CXCL-mediated signaling plays a key role in angiogenesis and tumor progression.
(Naphthalimide Analogue UNBS5162, NCI Thesaurus)
It can be used to study processes such as angiogenesis (growth of blood vessels).
(Nanoprobe, NCI Dictionary)
Tie2 is an endothelial cell specific receptor that is activated by angiopoietins, growth factors required for angiogenesis.
(Multikinase Inhibitor ARRY614, NCI Thesaurus)
Inhibition of these RTKs and their downstream signaling pathways may result in the inhibition of tumor angiogenesis and tumor cell proliferation in tumors overexpressing these RTKs.
(Multitargeted Tyrosine Kinase Inhibitor MGCD265, NCI Thesaurus)
This may result in the inhibition of tumor growth and angiogenesis, and tumor regression.
(Multitargeted Tyrosine Kinase Inhibitor XL647, NCI Thesaurus)
