| Health / Medical Topics |
Anti-A33 Monoclonal Antibody KRN330
A recombinant fully human monoclonal antibody directed against the human A33 antigen, with potential immunomodulatory and antineoplastic activity. Anti-A33 monoclonal antibody KRN330 recognizes and binds to the human A33 antigen, which may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against A33-positive colorectal cancers. A33 antigen, a 43 kDa transmembrane glycoprotein of the immunoglobulin superfamily, is highly and homogenously expressed in 95% of colorectal cancer cancers with only restricted expression in normal colonic mucosa and small bowel epithelia. (NCI Thesaurus)
YOU MAY ALSO LIKE
An antibody-drug conjugate composed of an antibody directed against 5T4 and conjugated, via the stable linker maleimidocaproyl (mc), to the microtubule inhibitor…
The branch of science concerned with origin and development of humans in all their physical, social, and cultural relationships.
Generated by the actions of humans.
Anthrax toxin receptor 1 (564 aa, ~63 kDa) is encoded by the human ANTXR1 gene. This protein plays a role in the…
One of the key causes of anthrax virulence is the action of three specific factors produced by the bacterium Bacillus anthracis. Even…
An infection caused by Bacillus anthracis bacteria. It may affect the lungs, gastrointestinal tract, or skin. Patients with lung infection present with…
