| Health / Medical Topics |
Anti-EGFL7 Monoclonal Antibody MEGF0444A
A humanized IgG1 monoclonal antibody directed against the epidermal growth factor-like domain multiple 7 (EGFL7) with potential antineoplastic activity. Anti-EGFL7 monoclonal antibody MEGF0444A binds to EGFL7, thereby preventing the activities of EGFL7 on endothelial cells and inhibiting the survival and migration of endothelial cells during angiogenesis. EGFL7, a vascular-restricted extracellular matrix protein which is upregulated during angiogenesis and which regulates vascular development, may be overexpressed on the cell surfaces of various solid tumor cell types. (NCI Thesaurus)
YOU MAY ALSO LIKE
An antibody that binds to an administered drug. Expression of these antibodies is thought to be induced by (repeated) drug administration. …
An agonist mouse monoclonal antibody directed against TRAIL death receptor type 5 (DR5) with potential antineoplastic activity. Anti-DR5 agonist monoclonal antibody TRA-8…
The determination of the amount of anti-double stranded DNA present in a sample.
An immunoconjugate of the anti-dopamine-b-hydroxylase monoclonal antibody covalently linked to the ribosome-inactivating protein (RIP) saporin derived from Saponaria officinalis. The monoclonal antibody…
The determination of the amount of anti-DNA antibodies present in a sample.
An antinuclear autoantibody directed against nuclear DNA.
