| Health / Medical Topics |
Anti-IL-1 alpha Monoclonal Antibody MABp1
A human IgG1 monoclonal antibody directed against interleukin-1 alpha (IL1a) with potential antineoplastic activity. Anti-IL-1 alpha monoclonal antibody MABp1 binds to IL1a and may prevent IL1a activity. In addition, this agent may induce antibody-dependent cellular cytotoxicity (ADCC) or complement-mediated killing (CMK). IL 1a, an inflammatory mediator, plays a key role in interleukin-mediated tumor cell activity such as metastasis and tumor cell invasion. (NCI Thesaurus)
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