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ANTINEOPLASTIC
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
Any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function
Synonyms:
antineoplastic; antineoplastic drug; cancer drug
Classified under:
Nouns denoting man-made objects
Hypernyms ("antineoplastic" is a kind of...):
cytotoxic drug (any drug that has a toxic effect on cells; commonly used in chemotherapy to inhibit the proliferation of cancerous cells)
Hyponyms (each of the following is a kind of "antineoplastic"):
alkylating agent (an antineoplastic drug used to treat some forms of cancer)
antimetabolite (an antineoplastic drug that inhibits the utilization of a metabolite)
antineoplastic antibiotic (an antibiotic drug used as an antineoplastic in chemotherapy)
asparaginase; Elspar (antineoplastic drug (trade name Elspar) sometimes used to treat lymphoblastic leukemia)
floxuridine (antineoplastic drug used to treat some cancers; can cause loss of hair)
lomustine (an antineoplastic drug often used to treat brain tumors or Hodgkin's disease)
Alkeran; melphalan (antineoplastic drug (trade name Alkeran) used to treat multiple myeloma and some other malignancies)
periwinkle plant derivative (an antineoplastic drug used to treat some forms of cancer)
procarbazine (an antineoplastic drug used to treat Hodgkin's disease)
thioguanine (an antineoplastic drug used to treat acute leukemias)
thiotepa (an antineoplastic drug used to treat certain malignancies)
Derivation:
antineoplastic (used in the treatment of cancer)
II. (adjective)
Sense 1
Meaning:
Used in the treatment of cancer
Example:
an antineoplastic effect
Synonyms:
anticancer; antineoplastic; antitumor; antitumour
Classified under:
Relational adjectives (pertainyms)
Pertainym:
neoplasm (an abnormal new mass of tissue that serves no purpose)
Derivation:
antineoplastic (any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function)
Context examples:
A phenylalanine derivative of nitrogen mustard with antineoplastic activity.
(Melphalan, NCI Thesaurus)
A propylene glycol-free intravenous formulation containing the hydrochloride salt of the nitrogen mustard phenylalanine derivative melphalan complexed with polyanionic sulfobutyl ether beta-cyclodextrin (SBE-CD) with potential antineoplastic activity.
(Melphalan Hydrochloride/Sulfobutyl Ether Beta-Cyclodextrin Complex, NCI Thesaurus)
A preparation of peripheral blood lymphocytes (PBLs) transduced with a retroviral vector encoding a T cell chimeric antigen receptor (CAR) specific for mesothelin with potential immunostimulatory and antineoplastic activities.
(Mesothelin-specific Chimeric Antigen Receptor-engineered Peripheral Blood Lymphocytes, NCI Thesaurus)
A cell-based cancer vaccine consisting of autologous dendritic cells (DCs) pulsed with mesothelioma tumor lysate with potential immunostimulating and antineoplastic activities.
(Mesothelioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine, NCI Thesaurus)
An inhibitor of MET tyrosine kinase with potential antineoplastic activity.
(MET Tyrosine Kinase Inhibitor BMS-777607, NCI Thesaurus)
An inhibitor of the receptor tyrosine kinase Met (hepatocyte growth factor receptor) with potential antineoplastic activity.
(MET Tyrosine Kinase Inhibitor EMD 1204831, NCI Thesaurus)
An oral suspension containing the thiopurine-derivative antimetabolite 6-mercaptopurine, with potential antineoplastic activity.
(Mercaptopurine Oral Suspension, NCI Thesaurus)
The anhydrous form of mercaptopurine, a thiopurine-derivative antimetabolite with antineoplastic and immunosuppressive activities.
(Mercaptopurine Anhydrous, NCI Thesaurus)
A water-soluble, positively charged fusion protein consisting of a luteinizing hormone releasing hormone (LHRH) receptor-targeting ligand conjugated to the membrane-disrupting peptide CLIP 71 with membrane-disrupting and potential antineoplastic activities.
(Membrane-Disrupting Peptide EP-100, NCI Thesaurus)
A menaquinone compound and form of vitamin K2 with potential antineoplastic activity.
(Menatetrenone, NCI Thesaurus)
