APF530

A controlled-release formulation of a biodegradable poly(ortho ester) polymer, encapsulating the indazole derivative granisetron, with antiemetic activity. Upon administration of APF530, the polymer slowly erodes and releases the active ingredient granisetron. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of nausea and vomiting over a sustained period of time. (NCI Thesaurus)

YOU MAY ALSO LIKE

APEX2 wt Allele

Human APEX2 wild-type allele is located in the vicinity of Xp11.21 and is approximately 7 kb in length. This allele, which encodes…

APEX2 Gene

This gene plays a role in DNA recognition and repair.

APEX1 wt Allele

Human APEX1 wild -type allele is located within 14q11.2-q12 and is approximately 13 kb in length. This allele, which encodes DNA-(apurinic or…

APEX1 Gene

This gene is involved in DNA repair processes.

Apex of the Tongue

The anterior extreme of the tongue which can be made pointed for sensing or probing and which rests against the lingual aspect…

Apex of the Prostate

The lowest part of the prostate gland adjacent to the superior fascia of the urogenital diaphragm.