| Health / Medical Topics |
APRT wt Allele
Human APRT wild-type allele is located within 16q24 and is approximately 2 kb in length. This allele, which encodes adenine phosphoribosyltransferase protein, is involved in an AMP purine salvage reaction that recycles adenine into nucleic acids by formation of AMP from adenine and 5-phosphoribosyl-1-pyrophosphate. Defects in the APRT gene cause APRT deficiency, a disorder also known as 2,8-dihydroxyadenine urolithiasis. (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene plays a role in the purine salvage pathway.
A single chain polypeptide isolated from bovine lung with antifibrinolytic and anti-inflammatory activities. As a broad-spectrum serine protease inhibitor, aprotinin bovine competitively…
The sodium salt form of aprosulate, a synthetic sulfated bis(lactobionic acid amide) derivative and heparin analogue with anticoagulant activity. Aprosulate is made…
A synthetic sulfated bis(lactobionic acid amide) derivative and heparin analogue with anticoagulant activity. Aprosulate is made up of two fully sulfated lactobionic…
A very rare congenital brain defect in which the cerebral cortex, striatum, globus pallidus, thalamus, hypothalamus, and eyes are absent or…
The fourth month of the year in the Gregorian calendar.
