Health / Medical Topics |
Argatroban
A synthetic derivative of L-arginine with antithrombotic activity. Argatroban is a univalent and direct inhibitor of fibrin-bound thrombin. This agent reversibly binds to the thrombin active site thereby preventing the thrombin-dependent reactions, which include conversion of fibrinogen to fibrin; the activation of factors V, VIII and XI; the activation of protein C; and platelet aggregation. Argatroban is highly selective for thrombin and is able to inhibit the action of both free and clot-associated thrombin. As a result, stabilization of blood clots and coagulation is inhibited. (NCI Thesaurus)
YOU MAY ALSO LIKE
The oil extracted from the kernels of Argania spinosa. Moroccan oil is used as a food ingredient and for cosmetic purposes. …
Human ARG1 wild-type allele is located 6q23 and is approximately 11 kb in length. This allele, which encodes arginase-1 protein, is involved…
This gene plays a role in the urea cycle.
The tartrate salt of arformoterol, the (R,R)-enantiomer of formoterol and a long-acting beta-2 adrenergic agonist with bronchodilator activity. Arformoterol selectively binds to…
A long-acting beta-2 adrenergic agonist and isomer of formoterol with bronchodilator activity. Arformoterol selectively binds to and activates beta-2 adrenergic receptors in…
The area of dark-colored skin on the breast that surrounds the nipple.