| Health / Medical Topics |
ARHGAP26 wt Allele
Human ARHGAP26 wild-type allele is located in the vicinity of 5q31 and is approximately 459 kb in length. This allele, which encodes Rho GTPase-activating protein 26, is involved in the modulation of signaling by both transforming protein RhoA and cell division control protein 42 homolog. Both mutation of the gene and a chromosomal translocation t(5;11)(q31;q23) of this gene and the MLL gene are associated with juvenile myelomonocytic leukemia. (NCI Thesaurus)
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