ARHGEF12 wt Allele

Human ARHGEF12 wild-type allele is located in the vicinity of 11q23.3 and is approximately 153 kb in length. This allele, which encodes Rho guanine nucleotide exchange factor 12 protein, is involved in the modulation of signaling that is mediated by both Rho-family GTPases or G-protein coupled receptors. The gene is involved in a translocation t(11;11)(q23;23) with the MLL gene which is associated with acute leukemia. (NCI Thesaurus)

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ARHGEF12 Gene

This gene plays a role in both G-protein coupled receptor- and Rho-mediated signaling.

ARHGEF1 wt Allele

Human ARHGEF1 wild-type allele is located in the vicinity of 19q13.13 and is approximately 24 kb in length. This allele, which encodes…

ARHGEF1 Gene

This gene plays a role in signal transduction and cell cycle control.

ARHGAP5 wt Allele

Human ARHGAP5 wild-type allele is located in the vicinity of 14q12 and is approximately 82 kb in length. This allele, which encodes…

ARHGAP5 Gene

This gene is involved in the regulation of GTPase activity.

ARHGAP29 wt Allele

Human ARHGAP29 wild-type allele is located in the vicinity of 1p22.1 and is approximately 126 kb in length. This allele, which encodes…