Library / English Dictionary

ATAXIA

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

Inability to coordinate voluntary muscle movements; unsteady movements and staggering gait

Synonyms:

ataxia; ataxy; dyssynergia; motor ataxia

Classified under:

Nouns denoting stable states of affairs

Hypernyms ("ataxia" is a kind of...):

nervous disorder; neurological disease; neurological disorder (a disorder of the nervous system)

Hyponyms (each of the following is a kind of "ataxia"):

Friedreich's ataxia; herediatry spinal ataxia (sclerosis of the posterior and lateral columns of the spinal cord; characterized by muscular weakness and abnormal gait; occurs in children)

hereditary cerebellar ataxia (nervous disorder of late childhood and early adulthood; characterized by ataxic gait and hesitating or explosive speech and nystagmus)

Holonyms ("ataxia" is a part of...):

spinocerebellar disorder (any of several congenital disorders marked by degeneration of the cerebellum and spinal cord resulting in spasticity and ataxia)

Derivation:

atactic; ataxic (lacking motor coordination; marked or caused by ataxia)

Credits

 Context examples: 

Signs and symptoms include progressive ataxia, dysarthria, and nystagmus.

(Paraneoplastic Cerebellar Degeneration, NCI Thesaurus)

Ataxia associated with chaotic multidirectional conjugate eye movements secondary to metastatic tumors to cerebellum.

(Paraneoplastic Opsoclonus Ataxia, NCI Thesaurus)

It is characterized by progressive neurologic deterioration manifested with ataxia, dementia, seizures, and dystonia.

(Niemann-Pick Disease, Type C, NCI Thesaurus)

Signs and symptoms include hepatosplenomegaly, pancytopenia, ataxia, dystonia, and dementia.

(Niemann-Pick Disease, NCI Thesaurus)

Mutation of the gene is associated with ataxia telangiectasia-like disorder.

(MRE11A wt Allele, NCI Thesaurus)

The neurologic disorders include movement disorders, ataxia, cognitive disturbances, personality changes, and seizures.

(Neuroacanthocytosis, NCI Thesaurus)

An orally available morpholino-pyrimidine-based inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase, with potential antineoplastic activity.

(ATR Kinase Inhibitor AZD6738, NCI Thesaurus)

Patients develop paralysis, ataxia and loss of sensation.

(Brown-Sequard Syndrome, NCI Thesaurus)

Defects in the ATM gene cause ataxia telangiectasia and contribute to certain cancers such as T-cell acute lymphoblastic leukemia, B-cell chronic lymphocytic leukemia and B-cell non-Hodgkin lymphomas.

(ATM wt Allele, NCI Thesaurus)

Mutation of the ATM gene causes the disease ataxia telangiectasia which involves an inherited predisposition to some cancers.

(ATM Signaling Pathway, NCI Thesaurus/BIOCARTA)