Atinumab

A monoclonal antibody directed against reticulon-4, with immunomodulating activity. Atinumab binds to reticulon-4, stimulating neurite outgrowth, which may prevent neuronal damage or may facilitate the regeneration of damaged neurons. Reticulon-4, also called Neurite outgrowth inhibitor or Nogo, is an inhibitor of neurite outgrowth and may prevent neuronal regeneration in the central nervous system. (NCI Thesaurus)

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Atigliflozin

A selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.

ATIC/ALK Fusion Protein

A fusion protein encoded by the ATIC/ALK fusion gene. This protein is comprised of the IMPCH and the dimerization domains of the…

ATIC/ALK Fusion Gene

A fusion gene that results from a chromosomal inversion inv(2)(p23q35) which fuses the first 7 exons of the ATIC gene with exon…

ATIC wt Allele

Human ATIC wild-type allele is located in the vicinity of 2q35 and is approximately 38 kb in length. This allele, which encodes…

ATIC Gene

This gene plays a role in purine biosynthesis.

Athymic nude mouse

A type of laboratory mouse that is hairless, lacks a normal thymus gland, and has a defective immune system because of a…