| Health / Medical Topics |
Aurora Kinase A
Aurora kinase A (403 aa, ~46 kDa) is encoded by the human AURKA gene. This protein is involved in mediating microtubular structure and facilitating chromosome segregation during mitosis and meiosis. (NCI Thesaurus)
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A substance being studied in the treatment of some types of cancer. It blocks certain enzymes (Aurora kinases) involved in cell division…
A small-molecule inhibitor of the serine-threonine kinase Aurora B with potential antineoplastic activity. Aurora B kinase inhibitor TAK-901 binds to and inhibits…
An orally bioavailable synthetic small molecule with potential antiangiogenic and antineoplastic activities. Aurora A kinase/tyrosine kinase inhibitor ENMD-2076 selectively binds to and…
An orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A, with potential antimitotic and antineoplastic activity. Aurora…
Human AURKC wild-type allele is located in the vicinity of 19q13.43 and is approximately 5 kb in length. This allele, which encodes…
This gene is involved in protein phosphorylation and mitosis.
