| Health / Medical Topics |
Aurora Kinase Inhibitor
Any substance that inhibits Aurora kinase, a serine/threonine kinase that is involved in mitotic spindle morphology, centrosome function, chromatid separation, and cytokinesis. Aurora kinases are overexpressed in a variety of human cancers. (NCI Thesaurus)
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Aurora kinase A (403 aa, ~46 kDa) is encoded by the human AURKA gene. This protein is involved in mediating microtubular structure…
A substance being studied in the treatment of some types of cancer. It blocks certain enzymes (Aurora kinases) involved in cell division…
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