Health / Medical Topics

    AXL wt Allele

    Human AXL wild-type allele is located in the vicinity of 19q13.2 and is approximately 43 kb in length. This allele, which encodes tyrosine-protein kinase receptor UFO protein is involved in extracellular matrix signal transduction and cellular proliferation stimulation. The AXL gene is a chronic myelogenous leukemia-associated oncogene and is also associated with colon cancer and melanoma. (NCI Thesaurus)




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