Health / Medical Topics |
Axon Guidance Pathway
Axon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are read by growth cone receptors, and signal transduction pathways downstream of these receptors converge onto the Rho GTPases to elicit changes in cytoskeletal organization that determine which way the growth cone will turn. (NCI Thesaurus/KEGG)
YOU MAY ALSO LIKE
A projection of a neuron that conducts electrical impulses away from the neuronal cell body.
A synapse between the axon of one neuron and the dendrite of another neuron.
A synapse between the axons of two neurons.
Human AXL wild-type allele is located in the vicinity of 19q13.2 and is approximately 43 kb in length. This allele, which encodes…
This gene plays a role in the tyrosine kinase receptor-mediated signal transduction pathway. The gene is also involved in cellular proliferation and…
A drug used to treat advanced renal cell carcinoma (the most common type of kidney cancer). It is used in patients who…