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Bacteria living in marine sponge produce toxic compounds found in man-made products
Researchers have discovered for the first time that a common marine sponge hosts bacteria that specialize in the production of toxic compounds nearly identical to man-made fire retardants, a finding that could help scientists better understand the human health implications of these common additives.
The new findings, by scientists at the Scripps Institution of Oceanography (SIO) at the University of California, San Diego, moved the research team a step closer to unraveling the mysteries of this powerful group of chemical compounds, known as polybrominated diphenyl ethers (PBDEs).
Manufacturers add PBDEs to foam, textiles, electronics and other products to make them less flammable. These industrial chemicals are powerful endocrine disruptors that mimic the activity of the human body's most active thyroid hormone.
Marine sponges obtain food and oxygen by filtering seawater through the pores and channels in their bodies. This constant flow of water means that these immobile animals host many bacteria, viruses and fungi in their complex microbiomes.
The research team collected 18 sponge samples for the study during two research expeditions to Guam. They then isolated the various components in the complex mixture of organisms from the sponge's tissues to identify the specific genes and enzymes that code for the production of PBDEs.
The genome "mining" approach along with metagenomic sequencing gave the scientists a way to connect the natural chemicals produced by organisms back to the enzymes that constructed them. (NSF)