Health / Medical Topics |
BCAS4 wt Allele
Human BCAS4 wild-type allele is located in the vicinity of 20q13.13 and is approximately 82 kb in length. This allele, which encodes breast carcinoma amplified sequence 4 protein, may be involved in both the progression of breast cancer and the regulation of vesicular trafficking. Some breast carcinomas are linked to either aberrant expression of the gene or a chromosomal translocation t(17;20)(q23;q13), which involves both this gene and the BCAS3 gene. (NCI Thesaurus)
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