| Health / Medical Topics |
BCR Protein
The 160 kD BCR phosphoprotein exhibits a unique serine/threonine kinase activity, at least two SH2 binding sites, and a C-terminal GTPase activating domain for p21(rac). The Philadelphia translocation produces a BCR-ABL1 chimeric product required for induction and maintenance of leukemia. (from OMIM 151410 and NCI) (NCI Thesaurus)
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