| Health / Medical Topics |
Betacellulin
Betacellulin is a member of the EGF family of growth factors; a potent mitogen for retinal pigment epithelia and vascular smooth muscle cells. Betacellulin effects may be mediated by the EGF receptor and/or related receptors. The precursor form is a type I membrane protein that contains one EGF-like domain and is synthesized in several tissues and tumor cells. Betacellulin from pancreatic beta cells could play a role in the vascular complications associated with diabetes. (from Swiss-Prot P35070 and NCI) (NCI Thesaurus)
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