| Health / Medical Topics |
Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Definition 1
An advanced phase of chronic myelogenous leukemia. It is characterized by: 1. the presence of blasts in the peripheral blood or bone marrow that are at least 20% of the peripheral blood white cells or of the nucleated cells in the bone marrow respectively, or 2. an extramedullary proliferation of blasts, and/or 3. when there are large aggregates and clusters of blasts in the bone marrow biopsy specimen (adapted from WHO, 2001). (NCI Thesaurus)
Definition 2
A phase of chronic myelogenous leukemia in which 20% or more of the cells in the blood or bone marrow are blast cells (immature blood cells). When tiredness, fever, and an enlarged spleen occur during the blastic phase, it is called blast crisis. (NCI Dictionary)
YOU MAY ALSO LIKE
The result of physical trauma sustained in an explosion.
The statistical probability of the number of alignments that are expected to occur by chance, in a database of a given size,…
A phase of chronic myelogenous leukemia in which tiredness, fever, and an enlarged spleen occur during the blastic phase, when more than…
The determination of the number of blast cells present in a blood sample.
Multiplication or reproduction by cell division of immature precursor cells that have not achieved a fully differentiated state.
Blast cells are in an immature (undifferentiated) stage in cellular development, occurring before the appearance of the definitive characteristics exhibited by fully…
