BMS-184476

Definition 1

A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called mitotic inhibitors. (NCI Dictionary)

Definition 2

A 7-methylthiomethyl ether derivative of paclitaxel with antineoplastic activity. BMS-184476 binds to and stabilizes the resulting microtubules, thereby inhibiting microtubule disassembly which results in cell- cycle arrest at the G2/M phase and apoptosis. (NCI Thesaurus)

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