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    BOLUS

    Pronunciation (US): Play  (GB): Play

     I. (noun) 

    Sense 1

    Meaning:

    A large pill; used especially in veterinary medicineplay

    Classified under:

    Nouns denoting man-made objects

    Hypernyms ("bolus" is a kind of...):

    lozenge; pill; tab; tablet (a dose of medicine in the form of a small pellet)

    Sense 2

    Meaning:

    A small round soft mass (as of chewed food)play

    Classified under:

    Nouns denoting two and three dimensional shapes

    Hypernyms ("bolus" is a kind of...):

    ball; globe; orb (an object with a spherical shape)

     II. (verb) 

    Sense 1

    Present simple (first person singular and plural, second person singular and plural, third person plural) of the verb bolus

    Credits

     Context examples: 

    A dosing unit equal to the amount of active ingredient(s) contained in a bolus.

    (Bolus Dosing Unit, NCI Thesaurus)

    A device designed to deliver a bolus into a system.

    (Bolus Mechanism Device Component, NCI Thesaurus)

    The cricopharyngeus muscle aids in swallowing by narrowing the lower part of the pharynx to move a bolus into the esophagus.

    (Cricopharyngeus Muscle, NCI Thesaurus)

    A regimen consisting of irinotecan, fluorouracil and leucovorin, all administered as bolus doses, and used for the treatment of advanced stage colorectal cancer.

    (IFL Regimen, NCI Thesaurus)

    Typically a baseline (fasting plasma or serum glucose) is drawn prior to the administration of the glucose bolus.

    (Glucose Tolerance Test, NCI Thesaurus)

    Method allows to maintain steady state plasma/serum medication levels, a smaller total daily dose of drug to achieve the same pharmacodynamic endpoint in comparison with intermittent or bolus infusion, and may result in lower toxicity.

    (Continuous Intravenous Infusion, NCI Thesaurus)

    Contrast or bolus agent.

    (Contrast Agent Name, NCI Thesaurus/DICOM)

    But the success has not hitherto been answerable, partly by some error in the quantum or composition, and partly by the perverseness of lads, to whom this bolus is so nauseous, that they generally steal aside, and discharge it upwards, before it can operate; neither have they been yet persuaded to use so long an abstinence, as the prescription requires.

    (Gulliver's Travels into several remote nations of the world, by Jonathan Swift)


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