BRCAPro

Pronunciation

Definition 1

A computer program that uses statistics to predict whether a person has an inherited mutation (change) in the BRCA1 and BRCA2 genes. People who have certain mutations in these genes have a higher than normal risk of breast, ovarian, prostate, and other types of cancer. The program is based on personal and family medical histories of breast and ovarian cancer. (NCI Dictionary)

Definition 2

A statistical model used to assess the probability that an individual carries a germline deleterious mutation of the BRCA1 and BRCA2 genes, based on family history of breast and ovarian cancer, including male breast cancer and bilateral synchronous and asynchronous diagnoses. (NCI Thesaurus)

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