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BREAKAGE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
The act of breaking something
Example:
the breakage was unavoidable
Synonyms:
Classified under:
Nouns denoting acts or actions
Hypernyms ("breakage" is a kind of...):
change of integrity (the act of changing the unity or wholeness of something)
Hyponyms (each of the following is a kind of "breakage"):
rupture (the act of making a sudden noisy break)
shattering; smashing (the act of breaking something into small pieces)
crack; cracking; fracture (the act of cracking something)
chip; chipping; splintering (the act of chipping something)
Derivation:
break (render inoperable or ineffective)
break (destroy the integrity of; usually by force; cause to separate into pieces or fragments)
break (break a piece from a whole)
break (ruin completely)
Sense 2
Meaning:
Reimbursement for goods damaged while in transit or in use
Classified under:
Nouns denoting possession and transfer of possession
Hypernyms ("breakage" is a kind of...):
reimbursement (compensation paid (to someone) for damages or losses or money already spent etc.)
Sense 3
Meaning:
The quantity broken
Example:
the total breakage was huge
Classified under:
Nouns denoting quantities and units of measure
Hypernyms ("breakage" is a kind of...):
indefinite quantity (an estimated quantity)
Context examples:
Any type of homology-dependent DNA strand exchange occuring during gametogenesis and involving synapsis of parental homologs, strand breakage and exchange of segments to yield unique combinations of genes in the gamete.
(Meiotic Recombination, NCI Thesaurus)
Issue associated with undesired damage or breakage of those materials used in device construction.
(Medical Device Break, Food and Drug Administration)
They are associated with chromosome breakage and other aberrations.
(Chromosome Fragile Site, NCI Thesaurus)
Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage.
(Doxorubicin, NCI Thesaurus)
Thereby leads to breakage of double-stranded DNA and consequently resulting in cell death.
(Anti-CD33 Immunotoxin, NCI Thesaurus)
Aminocamptothecin binds to the nuclear enzyme topoisomerase I, thereby inhibiting repair of single-strand DNA breakages.
(Aminocamptothecin, NCI Thesaurus)
The final breakage was first reported by Project Midas, an Antarctic research project based in the United Kingdom.
(Massive Iceberg Breaks Off from Antarctica, NASA)
A structural chromosomal abnormality caused by the spontaneous or induced breakage of a chromosome.
(Chromosome Breakage, NCI Thesaurus)
Additionally, in vitro studies demonstrate that this agent induces DNA breakage in a dose-dependent manner.
(Artesunate, NCI Thesaurus)
Screening for chromosomal breakage and rearrangement is used as a diagnostic tool in Fanconi anemia.
(Chromosomal Instability, NCI Thesaurus)
