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Bupivacaine
Pronunciation
Definition 1
A drug used to relieve pain by blocking signals at nerve endings. It is being studied in the relief of pain following surgery for cancer. It is a type of local anesthetic. Also called bupivacaine hydrochloride, Marcaine, and Sensorcaine. (NCI Dictionary)
Definition 2
An amide-type, long-acting local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation. (NCI Thesaurus)
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