Health / Medical Topics

    C3H/HeJ Mouse

    Definition 1

    Derived from the C3H progenitor strain that was passed to Heston in 1941 and to Jackson Lab in 1947. The C3H/HeJ mouse has an agouti coat color (genotype +, rd) and 90% of non-fostered offspring developed mammary tumors by 11 months or age. Fostered offspring have a high incidence of hepatomas. (NCI Thesaurus)

    Definition 2

    Derived from the C3H progenitor strain that was passed to Heston in 1941 and to Jackson Lab in 1947. The C3H/HeJ mouse has an agouti coat color and genotype +, rd. (NCI Thesaurus/CDISC)




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