Health / Medical Topics

    C-C Motif Chemokine 18

    Induced by glucocorticoids, PMA, IL-4, IL-13, and IL-10 and expressed by human CCL18 Gene (Intercrine Beta Family) in lung, lymph nodes, placenta, bone marrow, dendritic cells, and macrophages, secreted 89-aa 10-kDa (precursor) Small Inducible Cytokine A18, an immunoregulatory chemotactic cytokine for naive T cells, CD4+ and CD8+ T cells, and nonactivated lymphocytes involved in inflammatory processes s well as humoral and cell-mediated immunity. CCL18 may be involved in B cell migration into lymph node follicles. (NCI Thesaurus)




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