Health / Medical Topics

    c-FOS Antisense

    Definition 1

    An oligonucleotide targeting the c-fos gene which decreases c-fos target mRNA and protein expression, thereby inducing differentiation and inhibiting cell proliferation. (NCI Thesaurus)

    Definition 2

    A substance that has been studied in the treatment of cancer and is being studied in the treatment of rheumatoid arthritis and certain skin conditions. It blocks the production of a protein called c-fos, which helps control cell growth. This may kill cancer cells that need c-fos to grow. It is a type of antisense oligonucleotide. (NCI Dictionary)




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