C-Terminal Telopeptide Type I Collagen

This polypeptide is comprised of the carboxy-terminal portions of fibrillar collagen, which are joined through trivalent crosslinks and released during the degradation of mature type I collagen by matrix metalloproteinases. Increased serum concentrations of these peptides are associated with pathologies that cause bone lysis, such as multiple myeloma, osteolytic metastases, and rheumatoid arthritis. Increased blood levels of these peptides are associated with renal insufficiency. (NCI Thesaurus)

YOU MAY ALSO LIKE

C-Terminal Parathyroid Hormone Measurement

The determination of the amount of C-terminal parathyroid hormone present in a sample.

C-Reactive Protein Measurement

A quantitative measurement of the amount of C-reactive protein present in a sample.

C-Reactive Protein

C-reactive protein (224 aa, ~25 kDa) is encoded by the human CRP gene. This protein is cleaved during biological activation and is…

C-peptide suppression test

A test used to help diagnose a type of pancreatic tumor called an insulinoma. After fasting, the patient receives an injection of…

C-peptide Measurement

The determination of the amount of C-peptide present in a sample.

C-peptide

A substance made by the pancreas. C-peptide and insulin are both part of a larger molecule that gets split apart before being…