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Calcium-46 Chloride Aqueous Solution
Definition 1
An orally bioavailable aqueous solution containing the chloride salt of the radioisotope calcium-46 (46Ca) with phosphate-binding and radioisotopic activities. Upon administration of calcium-46 chloride aqueous solution, calcium-46 is preferentially taken up by osteoblasts, which generate mineralized osteoid containing calcium. Calcium-46 accumulation and turnover in bone can be measured with bone scintigraphy and urinary isotope excretion testing. (NCI Thesaurus)
Definition 2
A substance used to study the turnover of bone tissue in certain diseases, such as osteoporosis or cancer that has spread to the bone. Calcium-46 (46Ca) is a form of calcium. It is passed from the body in the urine. (NCI Dictionary)
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