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Camptothecin Analogue
Definition 1
Any substance based on the structure of camptothecin that stabilizes topoisomerase I-DNA covalent complexes, thereby causing DNA damage and apoptosis. (NCI Thesaurus)
Definition 2
An anticancer drug related in structure to camptothecin, a topoisomerase inhibitor. One such drug is aminocamptothecin. (NCI Dictionary)
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